Motif ID: FOX{I1,J2}.p2

Z-value: 1.733


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXI1chr5_+_169465478-0.332.1e-01Click!
FOXJ2chr12_+_80765080.185.2e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_159368690 8.581 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368721 7.732 TTC1
tetratricopeptide repeat domain 1
chr20_+_19818209 7.545 NM_018993
RIN2
Ras and Rab interactor 2
chr4_+_167013859 7.061 NM_012464
TLL1
tolloid-like 1
chr5_+_159368733 6.878 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr10_+_71231693 4.351 COL13A1
collagen, type XIII, alpha 1
chr10_+_71231649 4.280 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr5_-_54317102 3.710 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr5_-_59100194 3.501 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr7_+_151284396 3.195 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr19_+_57564981 3.051 NM_001145434
ZNF880
zinc finger protein 880
chr8_-_108579270 2.765 NM_001146
ANGPT1
angiopoietin 1
chr6_+_150304813 2.684 NM_025217
ULBP2
UL16 binding protein 2
chr7_-_87687276 2.659 SRI
sorcin
chr3_-_170970296 2.650 NM_032487
ARPM1
actin related protein M1
chr9_+_74956601 2.560 ANXA1
annexin A1
chr2_-_133145539 2.532 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr2_-_189752575 2.514 NM_000393
COL5A2
collagen, type V, alpha 2
chr4_-_70861301 2.461 NM_001891
CSN2
casein beta
chr2_-_134042500 2.410 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr3_+_11242666 2.300 NM_001098211
HRH1
histamine receptor H1
chr2_-_40593074 2.267 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr1_-_177378801 2.238 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr1_+_148747110 2.215 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr9_+_74956494 2.209 NM_000700
ANXA1
annexin A1
chr12_+_47584159 2.201 NM_033124
CCDC65
coiled-coil domain containing 65
chr6_+_121798443 2.176 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr22_+_44828338 2.161


chr1_+_242691295 2.154 NM_001130957
NM_173807
C1orf101

chromosome 1 open reading frame 101

chr6_+_153060722 2.129 NM_025107
MYCT1
myc target 1
chr7_-_87687302 1.946 NM_003130
SRI
sorcin
chr8_-_93176618 1.931 NM_001198629
NM_001198630
NM_001198632
NM_175635
RUNX1T1



runt-related transcription factor 1; translocated to, 1 (cyclin D-related)



chr2_+_201182187 1.916 AOX1
aldehyde oxidase 1
chr11_+_113672378 1.899 NNMT
nicotinamide N-methyltransferase
chr1_+_157246305 1.894 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr13_-_32757835 1.876 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_-_93181091 1.866 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_62280435 1.851 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr10_+_71232281 1.850 COL13A1
collagen, type XIII, alpha 1
chr4_+_86968069 1.821 ARHGAP24
Rho GTPase activating protein 24
chr11_+_113672407 1.808 NNMT
nicotinamide N-methyltransferase
chr3_-_115825742 1.788 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr9_+_77695334 1.777 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr4_+_154397975 1.746 TRIM2
tripartite motif containing 2
chr6_-_112682401 1.738 LAMA4
laminin, alpha 4
chr8_-_13416554 1.725 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr4_-_138673078 1.709 NM_019035
PCDH18
protocadherin 18
chr1_-_77457664 1.704 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr12_+_29193399 1.700 FAR2
fatty acyl CoA reductase 2
chr7_+_136203938 1.694 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr5_+_53787187 1.688 NM_006308
HSPB3
heat shock 27kDa protein 3
chr9_+_119506446 1.664 TLR4
toll-like receptor 4
chr6_-_112682459 1.633 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr22_-_43987978 1.615 KIAA0930
KIAA0930
chr9_+_119506428 1.611 TLR4
toll-like receptor 4
chr5_-_59100091 1.586 PDE4D
phosphodiesterase 4D, cAMP-specific
chr6_-_112682573 1.555 LAMA4
laminin, alpha 4
chr5_+_96237923 1.537 ERAP2
endoplasmic reticulum aminopeptidase 2
chr22_-_41366550 1.535 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr9_+_119506274 1.528 NM_138554
TLR4
toll-like receptor 4
chr1_+_156229686 1.502 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr9_-_16717887 1.500 BNC2
basonuclin 2
chr1_-_21373816 1.488 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr13_-_77391525 1.484


chr22_-_23500682 1.476 NM_001008496
PIWIL3
piwi-like 3 (Drosophila)
chr7_-_27186400 1.470 NM_153715
HOXA10
homeobox A10
chr7_+_113513828 1.470 FOXP2
forkhead box P2
chr4_-_186693574 1.454 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr9_+_74956614 1.426 ANXA1
annexin A1
chr11_+_113436438 1.426 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr14_+_78815406 1.413 NM_001105250
NM_138970
NRXN3

neurexin 3

chr10_-_14090459 1.412 FRMD4A
FERM domain containing 4A
chr12_+_118100977 1.412 NM_014365
HSPB8
heat shock 22kDa protein 8
chr13_-_85271329 1.409 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr20_+_19863716 1.406 RIN2
Ras and Rab interactor 2
chr1_+_84382529 1.405 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_-_14929991 1.402 NM_000900
NM_001190839
MGP

matrix Gla protein

chr5_+_54491702 1.388 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr9_-_116920232 1.385 NM_002160
TNC
tenascin C
chr1_+_82038669 1.380 NM_012302
LPHN2
latrophilin 2
chr3_-_170346760 1.378 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr6_+_116939500 1.376 NM_153711
FAM26E
family with sequence similarity 26, member E
chr19_-_42393225 1.371 NM_152279
ZNF585B
zinc finger protein 585B
chr3_-_191321367 1.366 LEPREL1
leprecan-like 1
chr10_-_90702490 1.358 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr1_+_84540921 1.352 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr9_+_129900637 1.350 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr3_-_130761967 1.341 PLXND1
plexin D1
chr2_+_151922350 1.327 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_150753601 1.320 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr2_+_36777406 1.316 VIT
vitrin
chr1_+_218768170 1.312 NM_018650
MARK1
MAP/microtubule affinity-regulating kinase 1
chr7_-_143213296 1.307 FAM115A
family with sequence similarity 115, member A
chr3_-_170347019 1.306 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr9_+_129900590 1.293 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr8_-_93177057 1.252 NM_001198625
NM_001198626
NM_001198627
NM_001198631
NM_001198634
NM_001198679
RUNX1T1





runt-related transcription factor 1; translocated to, 1 (cyclin D-related)





chr18_+_59705918 1.236 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr11_+_57547928 1.224 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr11_+_101488380 1.219 NM_001195045
YAP1
Yes-associated protein 1
chr5_+_55182963 1.214 NM_139017
IL31RA
interleukin 31 receptor A
chr12_-_9913199 1.203 CLEC2B
C-type lectin domain family 2, member B
chr9_-_4290028 1.198 NM_001042413
GLIS3
GLIS family zinc finger 3
chr14_+_57964462 1.181 NM_014749
KIAA0586
KIAA0586
chr1_+_218768146 1.178 MARK1
MAP/microtubule affinity-regulating kinase 1
chr8_-_93176819 1.160 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr9_+_12764988 1.159 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr3_+_116824840 1.151 NM_001130064
NM_002045
GAP43

growth associated protein 43

chr10_-_118022707 1.151 NM_001145453
GFRA1
GDNF family receptor alpha 1
chr14_+_50096603 1.146 ATL1
atlastin GTPase 1
chr17_+_26322168 1.141 RNF135
ring finger protein 135
chr2_+_12775814 1.138


chr9_-_4289915 1.137 GLIS3
GLIS family zinc finger 3
chr1_-_171441234 1.125 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr9_-_25668855 1.121 NM_001004125
TUSC1
tumor suppressor candidate 1
chr1_-_242073094 1.117 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chrX_-_50403412 1.115 SHROOM4
shroom family member 4
chr20_+_42644633 1.110 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr5_+_15553288 1.100 NM_012304
FBXL7
F-box and leucine-rich repeat protein 7
chr3_-_102194938 1.100 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr10_+_86174665 1.100 FAM190B
family with sequence similarity 190, member B
chr1_+_169421011 1.097 NM_001460
FMO2
flavin containing monooxygenase 2 (non-functional)
chr4_-_16509126 1.089 LDB2
LIM domain binding 2
chr6_+_49626071 1.088 NM_001145652
C6orf141
chromosome 6 open reading frame 141
chr2_+_33514896 1.079 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_66570683 1.075 PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_162795538 1.074 PBX1
pre-B-cell leukemia homeobox 1
chr8_-_13178399 1.064 DLC1
deleted in liver cancer 1
chr4_+_89518898 1.064 NM_001165136
NM_017912
HERC6

hect domain and RLD 6

chr19_-_19793512 1.064 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr4_+_15080586 1.061 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr7_+_113513600 1.060 FOXP2
forkhead box P2
chr12_+_46799279 1.059 NM_000289
PFKM
phosphofructokinase, muscle
chr14_+_57964148 1.058


chr1_+_84382562 1.055 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_+_15428820 1.055 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr19_-_14853166 1.055 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr3_-_145049853 1.054 NM_173653
SLC9A9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr17_+_26322081 1.054 NM_001184992
NM_032322
NM_197939
RNF135


ring finger protein 135


chr2_+_102320148 1.053 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr12_+_27066749 1.047 NM_004264
MED21
mediator complex subunit 21
chr12_+_27066768 1.030 MED21
mediator complex subunit 21
chrX_-_43717864 1.029 NM_000266
NDP
Norrie disease (pseudoglioma)
chr1_+_66570363 1.025 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_52421120 1.025 PRKG1
protein kinase, cGMP-dependent, type I
chr3_-_12561962 1.021 NM_001195279
LOC100129480
hypothetical protein LOC100129480
chr1_+_181421796 1.018 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr7_-_13995811 1.017 ETV1
ets variant 1
chr8_+_75066117 1.015 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr11_+_7997366 1.010 TUB
tubby homolog (mouse)
chr21_+_39117064 1.007 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr7_-_149960218 1.002 GIMAP6
GTPase, IMAP family member 6
chr10_-_31328426 0.985 NM_001143769
ZNF438
zinc finger protein 438
chr10_+_53744043 0.985 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr4_-_16509354 0.983 LDB2
LIM domain binding 2
chr12_-_69317441 0.982 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr8_-_23317577 0.981 LOXL2
lysyl oxidase-like 2
chr9_+_5500544 0.980 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr1_-_67366807 0.979 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr1_-_168310232 0.976 NM_014970
KIFAP3
kinesin-associated protein 3
chr11_-_72111027 0.972 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr15_+_37330176 0.968 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr3_+_46423682 0.967 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr6_+_151688327 0.960 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr12_-_50871953 0.959 NM_001081492
NM_182507
KRT80

keratin 80

chr3_+_108578877 0.956 NM_032600
CCDC54
coiled-coil domain containing 54
chr4_+_89519004 0.954 HERC6
hect domain and RLD 6
chr8_-_23317620 0.953 NM_002318
LOXL2
lysyl oxidase-like 2
chr3_-_188339882 0.949 NM_052969
RPL39L
ribosomal protein L39-like
chr19_-_9087438 0.948 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr11_-_101292462 0.945 NM_178127
ANGPTL5
angiopoietin-like 5
chr21_+_29439768 0.944 C21orf7
chromosome 21 open reading frame 7
chr8_-_24869945 0.944 NM_006158
NEFL
neurofilament, light polypeptide
chrX_+_101862297 0.930 NM_001142524
NM_001142525
NM_001142526
NM_001142527
NM_001142528
NM_030639
BHLHB9





basic helix-loop-helix domain containing, class B, 9





chr9_-_8723893 0.928 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr10_-_118021532 0.925 NM_145793
GFRA1
GDNF family receptor alpha 1
chr4_+_124537334 0.924 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_-_144991386 0.923 ZEB2
zinc finger E-box binding homeobox 2
chr4_-_16509446 0.922 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr9_-_87904844 0.917 NM_177937
GOLM1
golgi membrane protein 1
chr12_-_29827952 0.908 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_-_161439487 0.908 NM_003617
RGS5
regulator of G-protein signaling 5
chr4_+_119174947 0.908 NM_004784
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr22_-_34566367 0.907 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr18_-_21184824 0.903


chr3_-_21767819 0.899 NM_024697
ZNF385D
zinc finger protein 385D
chr9_+_674193 0.897


chr20_-_14266200 0.893 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr3_-_55489973 0.892 WNT5A
wingless-type MMTV integration site family, member 5A
chr12_+_55201854 0.891 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_-_151866147 0.888 NM_001024213
S100A13
S100 calcium binding protein A13
chr9_-_129381086 0.888 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr1_+_77105746 0.884 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr12_+_123339662 0.884 NM_181709
FAM101A
family with sequence similarity 101, member A
chr2_+_36777336 0.879 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr4_+_114330 0.873 ZNF718
zinc finger protein 718
chr15_+_65205107 0.870 NM_001145102
SMAD3
SMAD family member 3
chr1_+_169326641 0.866 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr19_-_56946911 0.862 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr21_-_42219849 0.858 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr4_-_138673014 0.851 PCDH18
protocadherin 18

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.02 2.70e-06 GO:0007608 sensory perception of smell
1.95 4.35e-06 GO:0007606 sensory perception of chemical stimulus
1.22 2.02e-05 GO:0032501 multicellular organismal process
1.35 8.54e-03 GO:0003008 system process
1.39 1.44e-02 GO:0050877 neurological system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 1.25e-06 GO:0005886 plasma membrane
1.26 1.29e-06 GO:0071944 cell periphery
1.71 4.26e-02 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.04 9.57e-07 GO:0004984 olfactory receptor activity
1.42 1.17e-03 GO:0004888 transmembrane receptor activity
1.49 5.92e-03 GO:0004930 G-protein coupled receptor activity
1.32 7.62e-03 GO:0004872 receptor activity